NanoKnife for prostate cancer: a precise and minimally invasive focal therapy

NanoKnife treatment represents a significant advancement in the management of localized prostate cancer. This innovative approach allows for the precise targeting of cancer cells while preserving surrounding healthy tissue.

At the Sioufi Urology Clinic, the NanoKnife is part of a modern vision of prostate cancer treatment, focused on oncological efficacy and the quality of life of patients.

What is NanoKnife treatment for prostate cancer?

The NanoKnife is a focal therapy based on irreversible electroporation. Unlike traditional treatments that use heat or radiation, the NanoKnife destroys cancer cells with controlled electrical pulses.

Principle of irreversible electroporation (IRE)

Irreversible electroporation creates permanent micropores in the membrane of cancer cells. These pores lead to the targeted death of tumour cells without damaging surrounding tissues such as nerves, blood vessels, or the urinary sphincter. This precision is one of the key advantages of the NanoKnife, especially when the tumour is located near sensitive structures.

For which patients is the NanoKnife recommended?

NanoKnife treatment is not suitable for all patients. Rigorous selection is essential to ensure optimal, safe results.

NanoKnife for localized prostate cancer

The NanoKnife is primarily recommended for men with localized prostate cancer, meaning cancer confined to a specific area of the prostate gland. It is particularly suitable for low- to intermediate-risk cancers.

Eligibility criteria based on MRI and targeted biopsies

The assessment typically includes:

• a multiparametric MRI of the prostate

• targeted biopsies by MRI-ultrasound fusion

• PSA level analysis

• the patient's general state of health

This assessment helps determine if the cancer can be effectively treated with a focal approach.

How is a NanoKnife treatment performed at the Sioufi Urology Clinic?

Advanced imaging treatment planning

Before treatment, meticulous planning is carried out based on MRI images and biopsy results. This step allows precise localization of the treatment area and planning of electrode placement.

NanoKnife Procedure Procedure

The procedure involves inserting thin electrodes into the prostate under image guidance. Electrical pulses are then delivered to destroy only the targeted cancerous tissue. The treatment is minimally invasive and generally well tolerated.

Follow-up after NanoKnife treatment

After treatment, medical follow-up is established. This includes clinical examinations, PSA tests and, if necessary, imaging examinations to ensure the effectiveness of the treatment and to monitor progress.

Advantages of NanoKnife compared to other prostate cancer treatments

Preservation of urinary continence

One of the major advantages of the NanoKnife is the preservation of urinary continence, an important issue for many patients.

Reducing the risk of erectile dysfunction

Thanks to the absence of heat and the precision of the treatment, the NanoKnife reduces the risk of erectile dysfunction compared to more aggressive treatments, such as radical surgery.

NanoKnife versus surgery and radiotherapy

Differences between focal therapy and radical prostatectomy

Radical prostatectomy and radiation therapy remain effective treatments for prostate cancer. However, they can lead to long-term side effects. The NanoKnife, as a focal therapy, aims to treat only the affected area while preserving the prostate and its essential functions.

Why choose Sioufi Urology Clinic for NanoKnife treatment?

The Sioufi Urology Clinic is distinguished by:

• recognized expertise in urology

• the use of advanced technologies

• a human, educational and personalized approach

• rapid access to specialist care

Where is NanoKnife treatment offered in Quebec?

NanoKnife in Montreal, Westmount and Châteauguay

NanoKnife treatment is offered at several clinics in the Montreal area, including in Montreal, Westmount and Châteauguay, facilitating access to care and medical follow-up.

The NanoKnife represents a modern, precise, and quality-of-life treatment option for some patients with localized prostate cancer. A specialist evaluation remains essential to determine if this treatment is appropriate for your situation.

Book your appointment online now or contact the clinic directly to speak to our team.